British Association of

Urological Pathology

British Association of Urological Pathology


The gross and microscopic features of typical examples of this tumor are well-known and need no elaboration here. However, one challenging aspect, problems caused when these lesions infarct, has been the subject of a recent report in the literature and is the only one I will consider briefly here (29). The extensive necrosis often makes it difficult to recognize that the neoplasm is an adenomatoid tumor. Additionally, the necrotic areas may be surrounded by a florid reactive process characterized by fibroblasts and myofibroblasts with plump nuclei, often with prominent nucleoli and occasional mitoses. Furthermore, this results in blurring of the usual relatively well-delineated periphery of an adenomatoid tumor potentially raising concern for a malignant neoplasm infiltrating the adjacent tissue. Recognition of ghost outlines of the typical formations of an adenomatoid tumor in the necrotic regions, and awareness of the phenomenon, are crucial in recognizing these cases as benign.